Agilent AdvanceBio Oligonucleotide Columns


To successfully separate trityl-off, deprotected oligonucleotides, HPLC columns need to have high resolving power and be robust enough to withstand challenging conditions.

If HPLC columns do not provide enough resolution, you cannot be sure your results are accurate. If columns are not robust, you will have to replace them frequently, which disrupts your workflow and increase your costs.

AdvanceBio oligonucleotide columns feature high efficiency, 2.7 μm superficially porous Poroshell particles. Using technology exclusive to Agilent, we chemically modify the particles to make them exceedingly resistant to high pH mobile phases. We also bond them with an end-capped C18 phase that delivers excellent selectivity for oligonucleotides. In addition, we test every batch of AdvanceBio oligonucleotide media with a resolution standard to ensure consistent performance.

AdvanceBio products are designed to deliver consistent, exceptional performance for the complete characterization and bioanalysis of proteins, antibodies, conjugates, new biological entities and biopharmaceuticals. 


View the product brochure to learn more.  

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  1. Agilent AdvanceBio Oligonucleotide 4.6 x 50 mm
    Agilent AdvanceBio Oligonucleotide, 4.6 x 50 mm, 2.7 um, LC column - BC (more info)
    NETA PART: 659950-702
    MFG. PART: 659950-702
    List Price $828.00 Your Price $828.00
  2. Agilent AdvanceBio Oligonucleotide 4.6 x 150 mm
    Agilent AdvanceBio Oligonucleotide, 4.6 x 150 mm, 2.7 um, LC column - BC (more info)
    NETA PART: 653950-702
    MFG. PART: 653950-702
    List Price $1,155.00 Your Price $1,155.00
  3. Agilent AdvanceBio Oligonucleotide 4.6 x 100 mm
    Agilent AdvanceBio Oligonucleotide, 4.6 x 100 mm, 2.7 um, LC column - BC (more info)
    NETA PART: 655950-702
    MFG. PART: 655950-702
    List Price $1,015.00 Your Price $1,015.00
  4. Agilent AdvanceBio Oligonucleotide 2.1 x 50 mm
    Agilent AdvanceBio Oligonucleotide, 2.1 x 50 mm, 2.7 um, LC column - BC (more info)
    NETA PART: 659750-702
    MFG. PART: 659750-702
    List Price $828.00 Your Price $828.00
  5. Agilent AdvanceBio Oligonucleotide 2.1 x 150 mm
    Agilent AdvanceBio Oligonucleotide, 2.1 x 150 mm, 2.7 um, LC column - BC (more info)
    NETA PART: 653750-702
    MFG. PART: 653750-702
    List Price $1,155.00 Your Price $1,155.00
  6. Agilent AdvanceBio Oligonucleotide 2.1 x 100 mm
    Agilent AdvanceBio Oligonucleotide, 2.1 x 100 mm, 2.7 um, LC column - BC (more info)
    NETA PART: 655750-702
    MFG. PART: 655750-702
    List Price $1,015.00 Your Price $1,015.00
  7. Agilent AdvanceBio Oligo 4.6 mm Fast Guard
    Agilent AdvanceBio Oligonucleotide, 4.6 mm, fast guard, LC column - BC (more info)
    NETA PART: 820750-921
    MFG. PART: 820750-921
    List Price $732.00 Your Price $732.00
  8. Agilent AdvanceBio Oligo 2.1 mm Fast Guard
    Agilent AdvanceBio Oligonucleotide, 2.1 mm, fast guard, LC column - BC (more info)
    NETA PART: 821725-921
    MFG. PART: 821725-921
    List Price $714.00 Your Price $714.00
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