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Active, N-terminal 6His-tagged, recombinant, human Pim-3, for use in Enzyme Assays.
Key Applications
Enzyme Assays
Biological Information
Source
expressed by baculovirus in Sf21 cells
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_001001852.2
Entrez Gene Summary
PIM3 belongs to a family of protooncogenes that encode serine/threonine protein kinases (Mikkers et al., 2004 [PubMed 15199164]).[supplied by OMIM]
Gene Symbol
PIM3
pim-3
Protein Target
Pim-3
Purification Method
Ni2+/NTA-agarose
Target Sub-Family
CAMK
UniProt Number
Q86V86
UniProt Summary
FUNCTION: SwissProt: Q86V86 # May be involved in cell cycle progression and anti- apoptosis process. Implicated in proliferation of human hepatoma cell lines. SIZE: 326 amino acids; 35863 Da TISSUE SPECIFICITY: Widely expressed. No expression in colon, thymus, and small intestine. Expressed in human hepatoma cell lines but not in normal liver tissues. SIMILARITY: SwissProt: Q86V86 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. & Contains 1 protein kinase domain.
Molecular Weight
39.6kDa
Product Usage Statements
Quality Assurance
routinely evaluated by phosphorylation of 250μM GGMEDIYFEFMGGKKK
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
