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Cayman Arachidonic Acid Maxspecв Standard; Purity- Greater Than O
NETA PART: | CAYM-10007268-1 |
MFG.PART: | 10007268-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Norwogonin is a polyhydroxy flavone that has been found in S. baicalensis and has diverse biological activities, including antioxidant, antiviral, and anticancer properties.,, It scavenges ABTS (Item No. ) and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. ) radicals with IC50 values of 1.24 and 35.61 μg/ml, respectively, in cell-free assays. Norwogonin inhibits cytopathic effects induced by enterovirus 71 (EV71) in infected Vero cells (IC50 = 31.83 μg/ml). It reduces the viability of MDA-MB-231, BT-549, HCC70, and HCC1806 triple-negative breast cancer (TNBC) cells (IC50s = 32.24, 56.2, 39.05, and 37.3 μM, respectively) but not the non-tumorigenic cell lines MCF-10A and AG11132 (IC50s = >100 μM for both). Norwogonin induces cell cycle arrest at the G1 and G2/M phases and increases apoptosis in MDA-MB-231 cells in a concentration-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 128304
- 5,7,8-Trihydroxyflavone
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.1 mg/ml
- Ethanol: 0.1 mg/ml
Shipping & Storage Information
SKU | CAYM-10007268-1 |
---|---|
Supplier Part Number | 10007268-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10007268m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 506-32-1 |