Cayman E-64; Purity- Greater Than Or Equal To 98%; Size- 50 Mg

E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities.^1,2,3,4,5 It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the aspartic protease pepsin.^2,1 E-64 (0.1-2 mg/ml) reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease.³ It is active against the FCR3 P. falciparum strain with an IC₅₀ value of 836 nM.⁴ E-64 (5-25 µM) reduces bone resorption in embryonic mouse bone explants.⁵

WARNING This product is not for human or veterinary use.