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Cayman Pik-93; Purity- Greater Than Or Equal To 98%; Size- 1 Mg;
Cayman Pik-93; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$32.00
Your Price
$32.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-10009212-1 |
MFG.PART: | 10009212-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIβ (PI4KIIIβ; IC50 = 19 nM). It is selective for PI4KIIIβ over PI4KIIIα and PI4KIIα (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110α, p110β, p110δ, and p110γ, respectively). PIK-93 reduces enteroviral RNA replication when used at a concentration of 125 nM in HeLa cells. It also inhibits the transport of ceramide from the endoplasmic reticulum to the Golgi apparatus.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[5-[4-chloro -3-[[(2-hy droxyethyl) amino]sulfon yl]phenyl]-4- methyl-2-thia zolyl]-acet amide
CAS Number
593960-11-3
Molecular Formula
C14H16ClN3O4S2
Formula Weight
389.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMSO: 5 mg/ml
- Ethanol: 0.25 mg/ml
λmax
203, 306 nm
SMILES
ClC1=C(S(NCCO)(=O)=O)C=C(C2=C(C)N=C(NC(C)=O)S2)C=C1
InChi Code
InChI=1S/C14H16ClN3O4S2/c1-8-13(23-14(17-8)18-9(2)20)10-3-4-11(15)12(7-10)24(21,22)16-5-6-19/h3-4,7,16,19H,5-6H2,1-2H3,(H,17,18,20)
InChi Key
JFVNFXCESCXMBC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10009212-1 |
---|---|
Supplier Part Number | 10009212-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10009212m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 593960-11-3 |