We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cell Signaling Marcksl1 (D4i9p) Rabbit mAb
Cell Signaling Marcksl1 (D4i9p) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$327.00
Your Price
$327.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CSIG-59568S |
| MFG.PART: | 59568S |
| UNSPSC: | 12352203 |
| Manufacturer: | Cell Signaling |
| Size | 100 µl |
| Reactivity | H M |
| Sensitivity | Endogenous |
| Molecular Weight (kDa) | 40 |
| Source/Isotype | Rabbit IgG |
| Application/Dilution | {Western Blotting: 1:1000} |
| Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | MARCKSL1 (D4I9P) Rabbit mAb recognizes endogenous levels of total MARCKSL1 protein. |
| Species Reactivity | Human, Mouse |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro186 of human MARCKSL1 protein. |
| Background | Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS/ MARCKS-like protein 1/ MacMARCKS/ MLP/ MRP) is a widely expressed membrane-bound PKC substrate involved in multiple cellular functions (1). MARCKSL1 is a MARCKS homolog that also serves as a substrate for PKC, and regulates cytoskeletal dynamics, migration, adhesion, and proliferation.In response to phosphorylation by JNK, MARCKSL1 regulates migration and actin dynamics in neuronal and prostate cancer cells (2). In the developing retina, MARCKSL1 regulates cell proliferation, and its expression decreases as retinal development progresses (3). Researchers have shown that MARCKSL1 may serve as a prognostic marker in lymph node-negative breast cancer (4). |
| SKU | CSIG-59568S |
|---|---|
| Supplier Part Number | 59568S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer Name | Cell Signaling |
| MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
| Temperature | -20C |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 5 Business Days |