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Cayman ()-L-Threo-Pdmp (Hydrochloride); Purity- Greater Than Or E
Cayman ()-L-Threo-Pdmp (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$65.00
Your Price
$65.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-10005278-1 |
MFG.PART: | 10005278-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Tozadenant is an adenosine A2A receptor antagonist (Kis = 11.5 and 6 nM for the human and rhesus monkey receptors, respectively). It increases the distance traveled and reduces contralateral asymmetry in the open field test in a rat model of Parkinsons disease induced by 6-OHDA (Item No. ) when administered at a dose of 30 mg/kg. Tozadenant (150 mg/kg) reverses locomotor deficits and restores novel object-stimulated locomotion in a marmoset model of MPTP-induced Parkinsons disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-hydroxy-N- [4-methoxy-7- (4-morpholinyl)- 2-benzo thiazolyl]-4- methyl-1- piperidine carboxamide
CAS Number
870070-55-6
Molecular Formula
C19H26N4O4S
Formula Weight
406.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/ml
- DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml
λmax
255, 284 nm
SMILES
COC1=C(N=C(NC(N2CCC(O)(C)CC2)=O)S3)C3=C(N4CCOCC4)C=C1
InChi Code
InChI=1S/C19H26N4O4S/c1-19(25)5-7-23(8-6-19)18(24)21-17-20-15-14(26-2)4-3-13(16(15)28-17)22-9-11-27-12-10-22/h3-4,25H,5-12H2,1-2H3,(H,20,21,24)
InChi Key
XNBRWUQWSKXMPW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10005278-1 |
---|---|
Supplier Part Number | 10005278-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10005278m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 161491-04-9 |