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Cayman Dimethylcurcumin; Purity- Greater Than Or Equal To 95%; Si
Cayman Dimethylcurcumin; Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$44.00
Your Price
$44.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-10008187-1 |
MFG.PART: | 10008187-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
C-DIM8 is a para-phenyl-substituted diindolylmethane (C-DIM) and an antagonist of the orphan receptor nuclear receptor-related protein 77 (Nur77). It inhibits reporter gene expression induced by the Nur77 agonist C-DIM5 (Item No. ) in PANC-28 cells when used at a concentration of 20 µM. C-DIM8 (10, 15, and 20 µM) reduces expression of BIRC5, the gene encoding survivin, in PANC-1 pancreatic cancer cells. In vivo, C-DIM8 (30 mg/kg) induces tumor cell apoptosis and reduces tumor volume in an L3.6pl pancreatic carcinoma mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(di-1H- indol-3-yl methyl)- phenol
CAS Number
151358-47-3
Synonyms
- DIM-C-pPhOH
- 1,1-bis-(3’-indolyl)-1-(p-hydroxyphenyl)methane
Molecular Formula
C23H18N2O
Formula Weight
338.4
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 15 mg/ml
- DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 10 mg/ml
λmax
212, 262 nm
SMILES
OC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1
InChi Code
InChI=1S/C23H18N2O/c26-16-11-9-15(10-12-16)23(19-13-24-21-7-3-1-5-17(19)21)20-14-25-22-8-4-2-6-18(20)22/h1-14,23-26H
InChi Key
QCPDFNWJBQMXLI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10008187-1 |
---|---|
Supplier Part Number | 10008187-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10008187m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 52328-98-0 |