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Cayman Niclosamide; Purity- Greater Than Or Equal To 95%; Size- 1
NETA PART: | CAYM-10649-100 |
MFG.PART: | 10649-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Niclosamide is a molluscicide. It is toxic to H. trivolvis snail eggs, juveniles, and adults (LC50s = 0.035, 0.044, and 0.11 mg/kg, respectively), as well as rainbow trout, white sucker, and fathead minnow (LC50s = 0.03, 0.09, and 0.11 mg/L, respectively)., Niclosamide induces cell cycle arrest at the G0/G1 phase and induces apoptosis in DU145 human prostate cancer cells in a concentration-dependent manner. It inhibits STAT3-induced gene expression in a reporter assay using HeLa human cervical cancer cells when used at a concentration of 5 µM. Niclosamide (1 µM) uncouples mitochondrial respiration and increases the oxygen consumption rate of NIH3T3 mouse fibroblasts. Dietary administration of niclosamide (1,500 ppm) reduces blood glucose and plasma insulin levels, as well as decreases liver weight and triglyceride levels, in a mouse model of high-fat diet-induced diabetes.
WARNING This product is not for human or veterinary use.
Technical Information
- BAY-6076
- BAY-73
- Bayer 6076
- Bayer 73
- HL 2448
- NSC 178296
- Ethanol: 0.5 mg/ml
Shipping & Storage Information
SKU | CAYM-10649-100 |
---|---|
Supplier Part Number | 10649-100 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10649m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 100 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 50-65-7 |