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Cayman Catharanthine; Purity- Greater Than Or Equal To 98%; Size-
Cayman Catharanthine; Purity- Greater Than Or Equal To 98%; Size- 100 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$71.00
Your Price
$71.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-11695-100 |
MFG.PART: | 11695-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Catharanthine is an indole alkaloid that has been found in C. roseus and has diverse biological activities.,,,, It is a precursor in the biosynthesis of the antimitotic agents vinblastine (Item No. ) and vincristine (Item No. ). Catharanthine (320 µM) inhibits microtubule assembly and the proliferation of HCT116 colon cancer cells (IC50 = 60 µg/ml)., It induces the release of amylase from mouse pancreas preparations when used at a concentration of 100 µM. Catharanthine (0.5-20 mg/kg) decreases blood pressure and heart rate in anesthetized normotensive rats.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2α,5β,6α)- 3,4- didehydro- ibogamine- 18β- carboxylic acid, methyl ester, 2R,3R-dihydroxybutanedioate (2:1)
CAS Number
4168-17-6
Synonyms
- (+)-
3,4- Didehydrocoronaridine
Molecular Formula
C21H24N2O2 • 1/2C4H6O6
Formula Weight
486.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
λmax
224, 283 nm
SMILES
CCC1=C[C@H]2C[C@]([C@]1([H])[N@@](C2)CC3)(C(OC)=O)C4=C3C5=C(N4)C=CC=C5.OC([C@@H]([C@@H](O)C(O)=O)O)=O.CCC6=C[C@H]7C[C@]([C@]6([H])[N@@](C7)CC8)(C(OC)=O)C9=C8C%10=C(N9)C=CC=C%10
InChi Code
InChI=1S/2C21H24N2O2.C4H6O6/c2*1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18;5-1(3(7)8)2(6)4(9)10/h2*4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t2*13-,19+,21-;1-,2-/m001/s1
InChi Key
OXIDCVCPXUNSCI-DWGLLIDUSA-N
Origin
Plant/Vinca rosea
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-11695-100 |
---|---|
Supplier Part Number | 11695-100 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11695m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CH |
ProductLine | CAYM |
Qty | 100 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 2468-21-5 |