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Cayman Jwh 250 N-(4-Hydroxypentyl) Metabolite-D5; Purity- Greater
Cayman Jwh 250 N-(4-Hydroxypentyl) Metabolite-D5; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D5); Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$356.00
Your Price
$356.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-11749-500 |
MFG.PART: | 11749-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
ONO-4059 is an inhibitor of Bruton’s tyrosine kinase (BTK; IC50 = 2.2 nM). It is selective for BTK over LCK, LYN, and Fyn at 1 µM. ONO-4059 inhibits B cell proliferation and activation in vitro and reduces tumor growth in a TMD8 mouse xenograft model.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-amino-7,9- dihydro-9- [(3R)-1-(1- oxo-2-butyn-1- yl)-3-pyrro lidinyl]-7-(4- phenoxyphenyl)- 8H-purin-8-one
CAS Number
1351636-18-4
Synonyms
- GS-4059
- ONO-WG-307
- Tirabrutinib
Molecular Formula
C25H22N6O3
Formula Weight
454.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
- Ethanol: 1 mg/ml
λmax
215 nm
SMILES
NC1=C2C(N([C@@]3([H])CN(CC3)C(C#CC)=O)C(N2C4=CC=C(C=C4)OC5=CC=CC=C5)=O)=NC=N1
InChi Code
InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1
InChi Key
SEJLPXCPMNSRAM-GOSISDBHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-11749-500 |
---|---|
Supplier Part Number | 11749-500 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11749m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 500 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 1782062-60-5 |