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Cayman Purpurin; Purity- Greater Than Or Equal To 95%; Size- 5 G
NETA PART: | CAYM-11752-5 |
MFG.PART: | 11752-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG; Item No. ) by attacking DAG at the sn-1 position. KT109 is a selective inhibitor of DAGLβ with an IC50 value of 42 nM. It demonstrates ~60-fold selectivity for DAGLβ over DAGLα, and negligible activity against other key enzymes involved in endocannabinoid signaling, including FAAH, MAGL, and ABHD11. KT109 has been shown to disrupt the lipid network involved in macrophage inflammatory responses, lowering 2-AG, as well as arachidonic acid (Item No. ) and eicosanoids, in mouse peritoneal macrophages.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
Shipping & Storage Information
SKU | CAYM-11752-5 |
---|---|
Supplier Part Number | 11752-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11752m.pdf |
Temperature | 22 |
Refrigerated-Frozen | Ambient |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 81-54-9 |