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Cayman Vincristine (Sulfate); Purity- Greater Than Or Equal To 95
Cayman Vincristine (Sulfate); Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$40.00
Your Price
$40.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-11764-5 |
MFG.PART: | 11764-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
TPI-1 is an inhibitor of protein tyrosine phosphatases. TPI-1 (10 ng/ml) increases phosphorylated substrates of the phosphatase SHP-1 in Jurkat T cells, including pLck-pY394, pZap70, and pSlp76. It is selective for SHP-1 over SHP-2, having low activity at the SHP-2 substrate pERK1/2. It increases pLck-pY394 levels by approximately 3.3-fold and increases the number of IFN-γ+ cells in mouse spleen ex vivo following a dose of approximately 3 mg/kg. Oral administration of TPI-1 (3 mg/kg per day) inhibits tumor growth in a B16 melanoma mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(2,5- dichloro phenyl)-2,5- cyclohexa diene-1,4- dione
CAS Number
79756-69-7
Synonyms
- Tyrosine Phosphatase Inhibitor 1
Molecular Formula
C12H6Cl2O2
Formula Weight
253.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 1 mg/ml
λmax
229 nm
SMILES
ClC1=C(C(C(C=C2)=O)=CC2=O)C=C(Cl)C=C1
InChi Code
InChI=1S/C12H6Cl2O2/c13-7-1-3-11(14)9(5-7)10-6-8(15)2-4-12(10)16/h1-6H
InChi Key
ZKHFYORNAYYOTM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-11764-5 |
---|---|
Supplier Part Number | 11764-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11764m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 2068-78-2 |