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Cayman Ur-144 N-(5-Hydroxypentyl) Betad-Glucuronide; Purity- Gr
NETA PART: | CAYM-11776-1 |
MFG.PART: | 11776-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Eurycomanone is a quassinoid originally isolated from E. longifolia that has diverse biological activities. It is active against the W2 and D6 clones of P. falciparum (IC50s = 0.015 and 0.026 µg/ml, respectively). Eurycomanone induces lipolysis in 3T3-L1 adipocytes with an EC50 value of 14.6 µM, an effect that can be blocked by the protein kinase A (PKA) inhibitor H-89 (Item No. ). It induces cell cycle arrest at the G2/M phase and apoptosis in HepG2 cells when used at a concentration of 5 µg/ml. It reduces estrogen release and increases testosterone release in isolated rat Leydig cell-rich testicular interstitial cell preparations when used at concentrations of 1 and 10 µM. Eurycomanone (1 mg/kg, i.p.) decreases gastric acid secretion and lesion size in rat models of indomethacin-, water immersion stress-, or pyloric ligation-induced ulcer formation.
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 339187
- Pasakbumin A
- DMSO: slightly soluble
Shipping & Storage Information
SKU | CAYM-11776-1 |
---|---|
Supplier Part Number | 11776-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11776m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1630023-01-6 |