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Cayman Ikk-16 (Hydrochloride); Purity- Greater Than Or Equal To 9
Cayman Ikk-16 (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$93.00
Your Price
$93.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-13313-5 |
MFG.PART: | 13313-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; Item No. ) from eosinophils (IC50 = 52 nM) and LTB4 (Item No. ) from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2R)-2-[4- [[[[2-(1,3- benzodioxol-5- yloxy)-3- pyridinyl] carbonyl] amino]methyl] -3-fluorophen oxy]-propanoic acid
CAS Number
445295-04-5
Molecular Formula
C23H19FN2O7
Formula Weight
454.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 3 mg/ml
- PBS (pH 7.2): 2 mg/ml
λmax
279 nm
SMILES
OC([C@@H](C)OC1=CC(F)=C(CNC(C2=CC=CN=C2OC3=CC=C(OCO4)C4=C3)=O)C=C1)=O
InChi Code
InChI=1S/C23H19FN2O7/c1-13(23(28)29)32-15-5-4-14(18(24)9-15)11-26-21(27)17-3-2-8-25-22(17)33-16-6-7-19-20(10-16)31-12-30-19/h2-10,13H,11-12H2,1H3,(H,26,27)(H,28,29)/t13-/m1/s1
InChi Key
CNIGFESSDPOCKS-CYBMUJFWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-13313-5 |
---|---|
Supplier Part Number | 13313-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13313m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1186195-62-9 |