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Cayman Ikk-16 (Hydrochloride); Purity- Greater Than Or Equal To 9
Cayman Ikk-16 (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$728.00
Your Price
$728.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13313-50 |
| MFG.PART: | 13313-50 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
IKK-16 is a potent inhibitor of IκB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKα, IKKβ, and IKK complex, respectively, in cell-free assays.1 It is effective in cells and in animals and has been used delineate the role of NF-κB signaling in diverse contexts.2,3,4,5 IKK-16 has also been reported to inhibit protein kinase D isoforms and the ATP-binding cassette (ABC) transporter ABCB1.6,7
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[4-
CAS Number
1186195-62-9
Synonyms
- IKK Inhibitor VII
Molecular Formula
C28H29N5OS • HCl
Formula Weight
520.1
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 5 mg/ml
- DMSO: 10 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
λmax
209, 263, 309 nm
SMILES
O=C(N1CCC(N2CCCC2)CC1)C3=CC=C(C=C3)NC4=NC=CC(C5=CC(C=CC=C6)=C6S5)=N4.Cl
InChi Code
InChI=1S/C28H29N5OS.ClH/c34-27(33-17-12-23(13-18-33)32-15-3-4-16-32)20-7-9-22(10-8-20)30-28-29-14-11-24(31-28)26-19-21-5-1-2-6-25(21)35-26;/h1-2,5-11,14,19,23H,3-4,12-13,15-18H2,(H,29,30,31);1H
InChi Key
XFVDIVQCZWDBCW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13313-50 |
|---|---|
| Supplier Part Number | 13313-50 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13313m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 50 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1186195-62-9 |