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Cayman Biotin-Nhs; Purity- Greater Than Or Equal To 95%; Size- 1
NETA PART: | CAYM-13315-1 |
MFG.PART: | 13315-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Alarelin is a peptide agonist of gonadotropin-releasing hormone (GnRH). It binds to the GnRH receptor (GnRHR) with a Kd value of 0.2 nM. Alarelin (6 ng, i.c.v.) decreases the expression of GnRH in the preoptic area and GnRHR in the posterior mediobasal hypothalamus (pMBH) of ovariectomized estradiol-treated rats, indicating an ultrashort negative feedback loop on GnRH and GnRHR gene expression. It induces desensitization in the pituitary and decreases serum estradiol levels and ovarian and uterine weight in neonatal and adult female rats. Alarelin reduces tumor growth in an HEC-1-B human endometrial carcinoma mouse xenograft model when administered at doses of 20, 40, and 80 µg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
- pGlu-HWSYALRP-NHEt
- [D-Ala6, des-Gly10]GnRH-ethylamide
- des-Gly GnRH
- DMF: 5 mg/ml
- DMSO: 5 mg/ml
- PBS (pH 7.2): 5 mg/ml
Shipping & Storage Information
SKU | CAYM-13315-1 |
---|---|
Supplier Part Number | 13315-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13315m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 35013-72-0 |