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Cayman Cgp 57380; Purity- Greater Than Or Equal To 95%; Size- 5 M
Cayman Cgp 57380; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$109.00
Your Price
$109.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13322-5 |
| MFG.PART: | 13322-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Acalabrutinib is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK). It can dose-dependently inhibit B cell receptor signaling in primary chronic lymphocytic leukemia cells. In kinase-inhibition assays, acalabrutinib was more selective than ibrutinib (Item No. ) for inhibiting BTK and did not inhibit EGFR, Itk, or Txk signaling.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-
CAS Number
1420477-60-6
Synonyms
- ACP-196
Molecular Formula
C26H23N7O2
Formula Weight
465.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 15 mg/ml
λmax
229, 283, 336 nm
SMILES
O=C(NC1=CC=CC=N1)C(C=C2)=CC=C2C3=C(C(N)=NC=C4)N4C([C@@H]5CCCN5C(C#CC)=O)=N3
InChi Code
InChI=1S/C26H23N7O2/c1-2-6-21(34)32-15-5-7-19(32)25-31-22(23-24(27)29-14-16-33(23)25)17-9-11-18(12-10-17)26(35)30-20-8-3-4-13-28-20/h3-4,8-14,16,19H,5,7,15H2,1H3,(H2,27,29)(H,28,30,35)/t19-/m0/s1
InChi Key
WDENQIQQYWYTPO-IBGZPJMESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13322-5 |
|---|---|
| Supplier Part Number | 13322-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13322m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 522629-08-9 |