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Cayman 8-Iso Prostaglandin E1; Purity- Greater Than Or Equal To 9
NETA PART: | CAYM-13360-1 |
MFG.PART: | 13360-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide (Item No. ) by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor (IC50 = 130 nM). It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH. Formulations containing methazolamide have been used in the treatment of glaucoma.
WARNING This product is not for human or veterinary use.
Technical Information
- DMSO: soluble
- Methanol: soluble
Shipping & Storage Information
SKU | CAYM-13360-1 |
---|---|
Supplier Part Number | 13360-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13360m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 21003-46-3 |