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Cayman Acs 67; Purity- Greater Than Or Equal To 95%; Size- 10 Mg
Cayman Acs 67; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$614.00
Your Price
$614.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-13619-10 |
MFG.PART: | 13619-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
CCT241533 is a selective inhibitor of checkpoint kinase 2 (Chk2; IC50 = 3 nM). In human cancer cell lines, CCT241533 blocks Chk2 activity and potentiates the cytotoxicity of the PARP inhibitors, rucaparib, AG-1447; (Item No. ) and olaparib (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R,4S)-rel- 4-[[2-(5- fluoro-2- hydroxy phenyl)-6,7- dimethoxy-4- quinazolinyl] amino]-α,α- dimethyl-3- pyrrolidine methanol, monohydro chloride
CAS Number
1431697-96-9
Molecular Formula
C23H27FN4O4 • HCl
Formula Weight
479.0
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 5 mg/ml
- PBS (pH 7.2): 500 µg/ml
λmax
222, 255, 334 nm
SMILES
FC1=CC(C2=NC(N[C@@H]3CNC[C@H]3C(C)(O)C)=C(C=C(OC)C(OC)=C4)C4=N2)=C(O)C=C1.Cl
InChi Code
InChI=1S/C23H27FN4O4.ClH/c1-23(2,30)15-10-25-11-17(15)27-21-13-8-19(31-3)20(32-4)9-16(13)26-22(28-21)14-7-12(24)5-6-18(14)29;/h5-9,15,17,25,29-30H,10-11H2,1-4H3,(H,26,27,28);1H/t15-,17-;/m1./s1
InChi Key
LAKJUTZIXHTMPC-SSPJITILSA-N
License
Sold under license from Cancer Research Technology, LTD.
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-13619-10 |
---|---|
Supplier Part Number | 13619-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13619m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1088434-86-9 |