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Cayman Alendronate (Sodium Hydrate); Purity- Greater Than Or Equa
Cayman Alendronate (Sodium Hydrate); Purity- Greater Than Or Equal To 95%; Size- 1 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$117.00
Your Price
$117.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13642-1 |
| MFG.PART: | 13642-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Alendronate is an amino bisphosphonate that inhibits farnesyl pyrophosphate (FPP) synthase (IC50 = 50 nM for the recombinant human enzyme). It inhibits bone resorption in a pit formation assay using isolated rat osteoclasts (IC50 = 2 nM). Alendronate (3 and 10 µM) reduces angiotensin II-induced collagen I synthesis in isolated rat cardiac fibroblasts. It prevents femoral bone mineral density loss in ovariectomized rats when administered at a dose of 5 mg/kg. Formulations containing alendronate have been used in the treatment of osteoporosis and Pagets disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
P,P-(4-amino-
CAS Number
121268-17-5
Synonyms
- Adronat
- Fosamax
- G-704650
- MK-217
Molecular Formula
C4H12NO7P2 • H6NaO3
Formula Weight
325.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- PBS (pH 7.2): 0.25 mg/ml
SMILES
NCCCC(P(O)([O-])=O)(O)P(O)(O)=O.[Na+]
InChi Code
InChI=1S/C4H13NO7P2.Na/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);/q;+1/p-1
InChi Key
CAKRAHQRJGUPIG-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13642-1 |
|---|---|
| Supplier Part Number | 13642-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13642m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 121268-17-5 |