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Cayman Gw 1929; Purity- Greater Than Or Equal To 98%; Size- 25 Mg
NETA PART: | CAYM-13689-25 |
MFG.PART: | 13689-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
TRX-818 is an anticancer compound., It inhibits vasculogenic mimicry network formation in C8161 and SK-MEL-28 melanoma cells when used at concentrations ranging from less than or equal to 5 to 10 nM. TRX-818 (10 nM) decreases pro-Nodal protein levels and Smad2 phosphorylation in C8161 cells. It reduces tumor volume with a minimum effective dose (MED) value of 50 mg/kg and decreases the number of vasculogenic mimicry channels in tumors when administered at a dose of 100 mg/kg in an HCT116 colon cancer mouse xenograft model. TRX-818 (7.5, 15, and 30 mg/kg) reduces tumor growth in a Hep3B mouse xenograft model in a dose-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 1 mg/ml
- PBS (pH 7.2): 0.5 mg/ml
Shipping & Storage Information
SKU | CAYM-13689-25 |
---|---|
Supplier Part Number | 13689-25 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13689m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 196808-24-9 |