We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Resazurin (Sodium Salt); Size- 5 G
Cayman Resazurin (Sodium Salt); Size- 5 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$63.00
Your Price
$63.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14322-5 |
| MFG.PART: | 14322-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR autophosphorylation in an HN-5 head and neck cancer mouse xenograft model. Formulations containing erlotinib have been used in the treatment of various cancers.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(3-ethynyl
CAS Number
183321-74-6
Synonyms
- NSC 718781
Molecular Formula
C22H23N3O4
Formula Weight
393.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50 mg/ml
- DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 0.25 mg/ml
λmax
247, 333 nm
SMILES
C#CC1=CC(NC2=NC=NC3=CC(OCCOC)=C(OCCOC)C=C32)=CC=C1
InChi Code
InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
InChi Key
AAKJLRGGTJKAMG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14322-5 |
|---|---|
| Supplier Part Number | 14322-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14322m.pdf |
| Temperature | 22 |
| Refrigerated-Frozen | Ambient |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 62758-13-8 |