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Cayman Efavirenz; Purity- Greater Than Or Equal To 98%; Size- 5 M
NETA PART: | CAYM-14412-5 |
MFG.PART: | 14412-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
UAMC-3203 is an inhibitor of ferroptosis that has an IC50 value of 10 nM for inhibition of erastin-induced ferroptosis in IMR-32 neuroblastoma cells. It decreases iron-induced plasma lactate dehydrogenase (LDH) levels in a mouse model of acute iron poisoning when administered at a dose of 20 µmol/kg. It is not toxic to mice following chronic administration of a 20 µmol/kg dose for four weeks. UAMC-3203 has increased solubility and a longer half-life in mouse, rat, and human microsomes and isolated plasma than the ferroptosis inhibitor ferrostatin-1 (Item No. ). In an in silico membrane dynamics study, UAMC-3203 was incorporated into a phospholipid bilayer.
WARNING This product is not for human or veterinary use.
Technical Information
- Ethanol: Soluble
Shipping & Storage Information
SKU | CAYM-14412-5 |
---|---|
Supplier Part Number | 14412-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14412m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 154598-52-4 |