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Cayman Efavirenz; Purity- Greater Than Or Equal To 98%; Size- 50
Cayman Efavirenz; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$477.00
Your Price
$477.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-14412-50 |
MFG.PART: | 14412-50 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to wild-type and mutant HIV-1 RTs (Kis = 2.93 and 3.85-56.5 nM, respectively).1 It inhibits wild-type and mutant HIV-1 viral replication in MT-4 human T lymphoid cells (IC95s = 1.5-1,500 nM). Efavirenz also prevents RNA plus-strand initiation with an IC50 value of 17 nM.2 In vivo, efavirenz reduces HIV-1 cDNA in spleen of HIV-1-challenged HIV-susceptible transgenic rats.3 Formulations containing efavirenz have been used in combination therapy for the treatment of HIV-1.4,5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(4S)- 6- chloro- 4- (2- cyclopropylethynyl)- 1,4- dihydro- 4- (trifluoromethyl)- 2H- 3,1- benzoxazin- 2- one
CAS Number
154598-52-4
Synonyms
- DMP 266
- EFV
- L-743,726
Molecular Formula
C14H9ClF3NO2
Formula Weight
315.7
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMSO: 14 mg/ml
- Ethanol: 20 mg/ml
- Ethanol:PBS(pH 7.2) (1:1): 0.50 mg/ml
λmax
247, 294 nm
SMILES
ClC1=CC=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1
InChi Code
InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)
InChi Key
XPOQHMRABVBWPR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-14412-50 |
---|---|
Supplier Part Number | 14412-50 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14412m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 50 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 154598-52-4 |