We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman 5-Fluoro Jwh 018 Adamantyl Analog; Purity- Greater Than Or
Cayman 5-Fluoro Jwh 018 Adamantyl Analog; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$356.00
Your Price
$356.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-14432-5 |
MFG.PART: | 14432-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
DG-051 is a potent, orally bioavailable leukotriene A4 hydrolase (LTA4H) inhibitor (Kd = 25 nM; IC50 = 47 nM), the enzyme that catalyzes the rate-determining step in the synthesis of LTB4 (Item No. ). However, it also inhibits the aminopeptidase activity of LTA4H with IC50 values of 72 and 150 nM when tested using the substrates L-alanine p-nitroanaline and prolyl-glycyl-proline peptide (PGP; Item No. ), respectively, potentially leading to PGP accumulation in vivo., DG-051 does not show any inhibitory activity against a panel of more than 50 additional aminopeptidases, ion channels, or HERG.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2S)-2-[[4-(4- chlorophenoxy) phenoxy]methyl]- 1-pyrrolidine butanoic acid, mono hydrochloride
CAS Number
929915-58-2
Molecular Formula
C21H24ClNO4 • HCl
Formula Weight
426.3
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- DMF: 20 mg/ml
- DMSO: 12.5 mg/ml
- Ethanol: 12.5 mg/ml
- PBS (pH 7.2): 2 mg/ml
λmax
231, 279 nm
SMILES
ClC1=CC=C(OC2=CC=C(OC[C@@H]3CCCN3CCCC(O)=O)C=C2)C=C1.Cl
InChi Code
InChI=1S/C21H24ClNO4.ClH/c22-16-5-7-19(8-6-16)27-20-11-9-18(10-12-20)26-15-17-3-1-13-23(17)14-2-4-21(24)25;/h5-12,17H,1-4,13-15H2,(H,24,25);1H/t17-;/m0./s1
InChi Key
UCPVOTSNNAVKNE-LMOVPXPDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
SKU | CAYM-14432-5 |
---|---|
Supplier Part Number | 14432-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14432m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 1364933-62-9 |