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Cayman Gly-Phe- Betanaphthylamide; Purity- Greater Than Or Equa
NETA PART: | CAYM-14634-100 |
MFG.PART: | 14634-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Osanetant is a neurokinin-3 (NK3) receptor antagonist (Ki = 0.21 nM in CHO cells expressing the human receptor). It is selective for NK3 over NK1 and NK2 receptors (Kis = >100 and 0.02 µM, respectively). Osanetant inhibits contractions and acetylcholine release induced by neurokinin B (Item No. ) in isolated guinea pig ileal strips in a concentration-dependent manner. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) neutrophil, eosinophil, and lymphocyte infiltration in an ovalbumin-sensitized mouse model of allergic asthma. Osanetant (5 and 10 mg/kg) increases the duration of social interaction, as well as reduces immobility time in the tonic immobility test, indicating anxiolytic-like and antidepressant-like activities, respectively, in gerbils.
WARNING This product is not for human or veterinary use.
Technical Information
- SR 142801
- DMSO: 15 mg/ml
Shipping & Storage Information
SKU | CAYM-14634-100 |
---|---|
Supplier Part Number | 14634-100 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14634m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 21438-66-4 |