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Cayman Aloesin; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
NETA PART: | CAYM-14649-5 |
MFG.PART: | 14649-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Cadazolid is an oxazolidinone-type antibiotic that has activity against a panel of C. difficile strains, including those resistant to fluoroquinolones and linezolid (Item No. ; MICs = 0.125-0.5 μg/ml). It inhibits toxin A and B formation in stationary-phase cultures and spore formation in late exponential cultures of the toxigenic C. difficile strain ATCC 9689. Cadazolid inhibits C. difficile protein synthesis (IC50s = 0.08-0.31 μg/ml) without affecting nucleic acid or cell wall synthesis (IC50s = 12-18.6 and >32 μg/ml, respectively). In vivo, cadazolid (1 and 10 mg/kg) increases survival in a mouse model of C. difficile-associated diarrhea (CDAD). It also confers 100% survival in a hamster model of CDAD when administered at doses greater than 3 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
- ACT-179811
- DMF: 30 mg/ml
- DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml
- DMSO: 20 mg/ml
Shipping & Storage Information
SKU | CAYM-14649-5 |
---|---|
Supplier Part Number | 14649-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14649m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 30861-27-9 |