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Cayman Aloesin; Purity- Greater Than Or Equal To 98%; Size- 500 M
NETA PART: | CAYM-14649-500 |
MFG.PART: | 14649-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.,,, It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells. Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells. In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. ) in mouse skin. Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.
WARNING This product is not for human or veterinary use.
Technical Information
- Indian Saffron
- Turmeric yellow
- 0.1 M NaOH: 3 mg/ml
- 10 mM Na2CO3: 50 µg/ml
- Acetone: 20 mg/ml
- Acetone:10 mM Na2CO3 (50:50): 5 mg/ml
- Water: 100 µg/ml
Shipping & Storage Information
SKU | CAYM-14649-500 |
---|---|
Supplier Part Number | 14649-500 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14649m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 500 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 30861-27-9 |