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Cayman Fostriecin (Sodium Salt); Purity- Greater Than Or Equal To
Cayman Fostriecin (Sodium Salt); Purity- Greater Than Or Equal To 95%; Size- 100 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$382.20
Your Price
$382.20
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14749-100 |
| MFG.PART: | 14749-100 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively)., It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM, respectively) and does not inhibit PP2B., Through its effects on protein phosphatases, fostriecin increases the level of histone H3 phosphorylation and may alter epigenetic regulation of cell proliferation. On a related note, fostriecin was first identified as an antitumor antibiotic.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(6R)-5,6-
CAS Number
87860-39-7
Synonyms
- Antibiotic CI-
920 - Phosphotrienin
Molecular Formula
C19H26O9P • Na
Formula Weight
452.4
Purity
≥95%
Formulation
A powder
Solubility
- Water: Soluble
SMILES
O=C1O[C@@H](/C=C/[C@@](C)(O)[C@H](OP([O-])(O)=O)C[C@@H](O)/C=C\C=C/C=C/CO)CC=C1.[Na+]
InChi Code
InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
InChi Key
XBUIKNRVGYFSHL-IAVQPKKASA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14749-100 |
|---|---|
| Supplier Part Number | 14749-100 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14749m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | AU |
| ProductLine | CAYM |
| Qty | 100 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 87860-39-7 |