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Cayman Moxifloxacin (Hydrochloride); Purity- Greater Than Or Equa
NETA PART: | CAYM-14830-100 |
MFG.PART: | 14830-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Moxifloxacin is a fluoroquinolone antibiotic.1 It is active against 390 clinical isolates of aerobic and anaerobic Gram-positive and Gram-negative bacteria (MIC90s = ≤0.25 µg/ml), as well as clinical isolates of methicillin-susceptible and -resistant S. aureus (MIC90s = 0.12 and 2 µg/ml, respectively).1,2 Moxifloxacin is an inhibitor of E. coli DNA gyrase that is selective for DNA gyrase over E. coli topoisomerase IV (IC50s = 0.51 and 38.8 mg/L, respectively, in cell-free assays).3 It prevents S. aureus- or P. aeruginosa-induced increases in bronchoalveolar lavage fluid (BALF) neutrophil infiltration and reduces S. aureus- or P. aeruginosa-induced increases in lung chemokine (C-X-C motif) ligand 1 (CXCL1) and IL-1β levels in mouse models of bacterial pneumonia when administered at a dose of 100 mg/kg twice per day for two days.4 Moxifloxacin (100 mg/kg) decreases the number of lung and spleen colony forming units (CFUs) in a mouse model of systemic M. tuberculosis infection.5 Formulations containing moxifloxacin have been used in the treatment of various bacterial infections.
WARNING This product is not for human or veterinary use.
Technical Information
- BAY 12-8039
- DMF: 3.33 mg/ml
- DMSO: 10 mg/ml
- PBS (pH 7.2): 0.2 mg/ml
Shipping & Storage Information
SKU | CAYM-14830-100 |
---|---|
Supplier Part Number | 14830-100 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14830m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 100 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 186826-86-8 |