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Cayman Sulfaphenazole; Purity- Greater Than Or Equal To 98%; Size
NETA PART: | CAYM-14844-5 |
MFG.PART: | 14844-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Deoxycholic acid (DCA) is a secondary bile acid that is formed via microbial transformation of cholic acid (Item No. ) in the colon. It can be conjugated to glycine or taurine (Item No. ) to produce glycodeoxycholic acid (GDCA; Item No. ) or taurodeoxycholic acid (TDCA; Item No. ), respectively, in hepatocytes.,, DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; Item No. ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 µM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer.
WARNING This product is not for human or veterinary use.
Technical Information
- DCA
- Sodium Deoxycholate
- DMF: 5 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 15 mg/ml
- PBS (pH 7.2): 1 mg/ml
Shipping & Storage Information
SKU | CAYM-14844-5 |
---|---|
Supplier Part Number | 14844-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14844m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 526-08-9 |