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Cayman Pf-573228; Purity- Greater Than Or Equal To 95%; Size- 1 M
NETA PART: | CAYM-14924-1 |
MFG.PART: | 14924-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Galanin is a neuropeptide with diverse biological activities.,,,, It inhibits forskolin-induced cAMP production in cells expressing GAL1 or GAL3 receptors (EC50s = 31.6 and 91 nM, respectively) and stimulates inositol phosphate accumulation in cells expressing GAL2 receptors (EC50 = 173.3 nM). Galanin binds to and inhibits contraction of guinea pig gastric smooth muscle cells induced by carbachol (Item No. ; IC50s = 7.9 and 4 nM, respectively). In vivo, Galanin (6 nmol, i.c.v.) increases feeding behavior in rats and increases latency to hindpaw withdrawal in response to heat and mechanical stimulation in a rat model of carrageenin-induced inflammation when administered at a dose of 2 nmol injected into the nucleus accumbens., Galanin (5 μg, i.c.v.) also inhibits acetylcholine (Item No. ) release induced by scopolamine in the ventral hippocampus of freely moving rats.
WARNING This product is not for human or veterinary use.
Technical Information
- GAL (rat, mouse)
- Galanin (1-29) (rat, mouse)
- Water: 1 mg/ml
Shipping & Storage Information
SKU | CAYM-14924-1 |
---|---|
Supplier Part Number | 14924-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14924m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 869288-64-2 |