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Cayman Doxorubicin (Hydrochloride); Purity- Greater Than Or Equal
Cayman Doxorubicin (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$32.00
Your Price
$32.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-15007-5 |
| MFG.PART: | 15007-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid (CA; Item No. ) and chenodeoxycholic acid (CDCA; Item No. )., It is formed via the oxidation of cholesterol (Item No. ) by cholesterol 7α-hydroxylase/CYP7A1 in rat liver microsomes. 7α-hydroxy Cholesterol (40 µM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). It increases secretion of chemokine (C-C motif) ligand 2 (CCL2) and matrix metalloproteinase-9 (MMP-9) in serum-deprived THP-1 cells when used at a concentration of 5 µg/ml. 7α-hydroxy Cholesterol has been found in macrophages isolated from atherosclerotic lesions in rabbits fed a high-cholesterol diet.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
cholest-5-ene
CAS Number
566-26-7
Molecular Formula
C27H46O2
Formula Weight
402.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/ml
- DMSO: 0.1 mg/ml
- Ethanol: 20 mg/ml
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
SMILES
O[C@H](C1)CC[C@@]2(C)C1=C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)C
InChi Code
InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1
InChi Key
OYXZMSRRJOYLLO-RVOWOUOISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-15007-5 |
|---|---|
| Supplier Part Number | 15007-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/15007m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 25316-40-9 |