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Cayman Exemestane; Purity- Greater Than Or Equal To 95%; Size- 25
NETA PART: | CAYM-15008-25 |
MFG.PART: | 15008-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
GW 842166X is a cannabinoid 2 (CB2) receptor agonist. It increases intracellular calcium mobilization induced by the CB receptor agonist CP 55,940 (Item No. ) in HEK cells co-expressing a chimeric Gαq/05 protein and the human CB2 receptor (EC50 = 7.78 µM). GW 842166X is selective for CB2 over the CB1 receptor (IC50s = 0.133 and >25 µM, respectively). It inhibits LPS-induced production of inducible nitric oxide synthase (iNOS), as well as reduces LPS-induced phosphorylation of ERK1/2 in BV-2 microglia cells when used at a concentration of 100 nM. GW 842166X inhibits hyperalgesia in a rat model of inflammatory pain induced by complete Freund’s adjuvant (ED50 = 0.1 mg/kg).
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 20 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 0.3 mg/ml
Shipping & Storage Information
SKU | CAYM-15008-25 |
---|---|
Supplier Part Number | 15008-25 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/15008m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 107868-30-4 |