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Cayman Torcetrapib; Purity- Greater Than Or Equal To 98%; Size- 5
Cayman Torcetrapib; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$101.85
Your Price
$101.85
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-15028-5 |
MFG.PART: | 15028-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Torcetrapib is an inhibitor of cholesteryl ester transfer protein (CETP; IC50s = 47 and 51 nM for cholesteryl and triglyceride transfer, respectively).1 It is selective for CETP over phospholipid transfer protein (PLTP), lecithin:cholesterol acyltransferase (LCAT), and hepatic and lipoprotein lipases at 10 µM. Torcetrapib (30 mg/kg) inhibits CETP activity and increases HDL cholesterol levels in serum from transgenic mice expressing human CETP and ApoA1.2 It increases mean arterial blood pressure in Zucker fa/fa diabetic rats when administered at doses of 60 and 200 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4S- [[[3,5- bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]- 2R- ethyl- 3,4- dihydro- 6- (trifluoromethyl)- 1(2H)- quinolinecarboxylic acid, ethyl ester
CAS Number
262352-17-0
Synonyms
- CP 529,414
- (–)-Torcetrapib
Molecular Formula
C26H25F9N2O4
Formula Weight
600.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 10 mg/ml
λmax
251 nm
SMILES
O=C(OC)N(CC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)[C@H]2C[C@@H](CC)N(C(OCC)=O)C3=CC=C(C(F)(F)F)C=C32
InChi Code
InChI=1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1
InChi Key
CMSGWTNRGKRWGS-NQIIRXRSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-15028-5 |
---|---|
Supplier Part Number | 15028-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/15028m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 262352-17-0 |