Cayman Glp-1 (7-36) Amide (Trifluoroacetate Salt); Size- 5 Mg

Prednisolone is a glucocorticoid and mineralocorticoid receptor agonist and an active metabolite of the prodrugs and synthetic glucocorticoids prednisolone phosphate (Item No. ) and prednisone (Item No. ).^,, It selectively binds to the glucocorticoid and mineralocorticoid receptors over the progesterone, androgen, and estrogen receptors (K_is = 2.4, 37, >5,000, 2,762, and >1,000 nM, respectively) and induces transactivation in reporter assays using CV-1 cells expressing the human glucocorticoid receptor or human mineralocorticoid receptor (EC₅₀s = 6.9 and 3.78 nM, respectively).^, Prednisolone reduces pulmonary eosinophil infiltration in a rat model of sephadex-induced asthma (ED₅₀ = 1.2 mg/kg). Formulations containing prednisolone have been used as anti-inflammatory or immunosuppressive agents.

WARNING This product is not for human or veterinary use.