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Cayman Glp-1 (7-36) Amide (Trifluoroacetate Salt); Size- 500 Micr
NETA PART: | CAYM-15069-500 |
MFG.PART: | 15069-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Sarpogrelate is a selective antagonist of the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2B, and 5-HT2C (Kis = 3.02, 269, and 37.2 nM, respectively, for human recombinant receptors expressed in CHO-K1 cells). It is selective for 5-HT2 (Ki = 70.8 nM) over 5-HT1 (Ki = >26,000 nM), α1-, α2-, and β-adrenergic (Kis = 640-123,800 nM), and muscarinic receptors (Ki = >40,000 nM). In vitro, it inhibits aggregation of rat whole blood induced by collagen, 5-HT (Item No. ) with collagen, and 5-HT with ADP (Item No. ; IC50s = 57.7, 0.56, and 22.7 μM, respectively). In vivo, it inhibits leukocyte-endothelial interactions in the femoral artery induced by a high-fat high-fructose diet (HFFD) in mice when administered at a dose of 5 mg/kg per day. Sarpogrelate (5 mg/kg per day) decreases ventricular hypertrophy and infarct size in a rat model of myocardial infarction.
WARNING This product is not for human or veterinary use.
Technical Information
- MCI-9042
- DMF: 33 mg/ml
- DMSO: 33 mg/ml
- PBS (pH 7.2): 0.33 mg/ml
Shipping & Storage Information
SKU | CAYM-15069-500 |
---|---|
Supplier Part Number | 15069-500 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/15069m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 500 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |