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Cayman Bay 85-3934; Purity- Greater Than Or Equal To 95%; Size- 1
NETA PART: | CAYM-15297-10 |
MFG.PART: | 15297-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
BAY 85-3934 is a pan-inhibitor of hypoxia-inducible factor prolyl hydroxylases (HIF-PH; IC50s = 0.48, 0.28, and 0.45 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively).1 It stabilizes HIF-1α and HIF-2α levels in HeLa cells in a concentration- and time-dependent manner. BAY 85-3934 (50 µM) induces cell-cycle arrest at the G2/S phase in MDA-MB-231 breast cancer cells.2 It decreases lactate dehydrogenase (LDH) release from PC12 cells in an in vitro model of ischemia induced by oxygen-glucose deprivation when used at a concentration of 100 µM.3 BAY 85-3934 (5 mg/kg) increases plasma erythropoietin and hemoglobin levels, as well as packed cell volume, in a rat model of gentamicin-induced kidney failure.1
WARNING This product is not for human or veterinary use.
Technical Information
- Molidustat
- Ethanol: slightly soluble
- Methanol: slightly soluble
Shipping & Storage Information
SKU | CAYM-15297-10 |
---|---|
Supplier Part Number | 15297-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/15297m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1154028-82-6 |