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Cayman (В±)8-Hdha; Purity- Greater Than Or Equal To 98%; Size- 25
NETA PART: | CAYM-33350-25 |
MFG.PART: | 33350-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
PSB-603 is an antagonist of the adenosine A2B receptor (Ki = 0.553 nM). It is selective for adenosine A2B over A1, A2A, and A3 receptors (Kis = >10,000 nM). It reduces intracellular calcium concentrations in Jurkat T cells expressing the human A2B receptor (IC50 = 1.13 nM). PSB-603 reduces Zika viral plaque formation (IC50 = 43.8 nM) without affecting cell viability of A549 cells when used at concentrations up to 1 µM. In vivo, PSB-603 (0.25 µg/head, i.p.) delays tumor growth and reduces tumor volume and the number of pulmonary metastases in the B16 mouse model of melanoma via inhibition of induction of regulatory T cells.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 5 mg/ml
- DMSO: 5 mg/ml
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
- Ethanol: slightly soluble
Shipping & Storage Information
SKU | CAYM-33350-25 |
---|---|
Supplier Part Number | 33350-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer Name | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/33350m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 90780-54-4 |