The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Millipore Anti-Integrin Α1 Antibody, Clone 5e8d9 Is An Antibody Against Integrin Α1 For Use In Ic, Neut. - Mill (Additional S&H or Hazmat Fees May Apply)
Anti-Integrin α1 Antibody, clone 5E8D9 is an antibody against Integrin α1 for use in IC, NEUT.
Key Applications
Immunocytochemistry
Neutralizing
Biological Information
Immunogen
Purified human integrinα1
Clone
5E8D9
Host
Mouse
Specificity
integrinα1
Isotype
IgG2a
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NM_181501
Entrez Gene Summary
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Gene Symbol
ITGA1
CD49a
VLA1
VLA-1
Purification Method
Protein A chromatography
UniProt Number
P56199
UniProt Summary
FUNCTION: SwissProt: P56199 # Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. SIZE: 1179 amino acids; 130848 Da SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. DOMAIN: SwissProt: P56199 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.
Molecular Weight
150kDa
Product Usage Statements
Quality Assurance
routinely evaluated on cold ethanol fixed cells in immunocytochemistry
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
