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AG Scientific Etoposide, 100 MG
AG Scientific Etoposide (100 MG) is a Topoisomerase II inhibitor derived from podophyllotoxin. It induces apoptosis, autophagy in various cell lines & has a antitumor property so can be used for treatment of cancer (Addtl S&H Or Haz Fees May Apply) - AG
List Price
$86.22
Your Price
$86.22
HOW MUCH YOU SAVE:
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NETA PART: | RPI-E-2004-100MG |
MFG.PART: | E-2004-100MG |
UNSPSC: | 12352200 |
Manufacturer: | AG Scientific |
AG Scientific
(Additional S&H Or Hazmat Fees May Apply) - AG
Description:
Etoposide is a Topoisomerase II inhibitor derived from podophyllotoxin. It induces apoptosis, autophagy in various cell lines and has a antitumor property so can be used for treatment of cancer. This reagent suppresses DNA synthesis and blocks specific cell cycles because it helps to break double-strand DNA by generating transient double-stranded breaks in the double helix.
Its antitumor property is explained by activation of tumor suppressor p53 and inhibition of synthesis of oncoprotein Mdm2 and overexpress Mdm2 to promote apoptosis.
Applications:
- Anti-tumor reagent
- Preparation of drug stock solution in dimethyl sulfoxide (DMSO)
- DNA damage inducer
References:
- “Etoposide, Topoisomerase II and Cancer”
- “Cellular response to etoposide treatment”
- “β-Actin facilitates etoposide-induced p53 nuclear import”
(Additional S&H Or Hazmat Fees May Apply) - AG
SKU | RPI-E-2004-100MG |
---|---|
Supplier Part Number | E-2004-100MG |
UM | EA |
UNSPSC | 12352200 |
Manufacturer Name | AG Scientific |
MSDS URL | https://agscientific.com/system/product_documents/E-2004%2C%20Etoposide%2C%20SDS%202022_r01_1.pdf |
Temperature | -20°C |
Refrigerated-Frozen | Y |
CountryOfOrigin | China |
ProductLine | AG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 5.00 |
Lead Time | 5 Business Days |
Hazardous | N |
CAS Number | 33419-42-0 |