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Corning Life Sciences

Enhance cell adhesion and protein absorption with synthetic Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL). These compounds modify surface charges, supporting various cell types, neurite outgrowth, and CNS primary cell survival

Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Applications include:

  • Attachment and spreading of a variety of cell types
  • Cell differentiation and neurite outgrowth
  • Attachment of fastidious transfected cell lines
  • Support survival of primary neurons in culture
  • Serum-free or reduced-serum culture

Source

  • PDL, synthetic (MW 75-150 kD)
  • PLL, synthetic (MW 30-70 kD)

Quality Control

  • Tested for ability to promote firm attachment of RCG cells
  • Tested and found negative for bacteria and fungi

Storage

  • 4°C to 30°C under dry conditions.

  • GROUP SKU : CFAL-16
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    • Meet bioanalytical-grade requirements and provide unsurpassed performance in critical research applications
    • Exceptionally strong—Industry leading centrifugation rating of 16,000 RCF (50 mL polypropylene)
    • Unique double threaded cap design reducing cross threading and leakage
    • Easy-to-read graduations
    • Consistent biological and physical properties
    • Ideal for long-term cryogenic storage of specimens at -80°C (15 to 225 mL polypropylene tubes)
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