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The antibody recognizes the CD57 carbohydrate epitope present on several surface molecules. In the nervous system this epitope is particularly prominent on myelin-associated glycoprotein (MAG) (Funaro, 1997). The eptope for TB01 is neuraminidase- and bromelaine-sensitive, but trypsin-resistant (Funaro, 1997). Anti-CD57, TBO1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD57 (Funaro, 1997).
Product Information
Format
FITC
Control
PBMCs
Presentation
Purified Mouse monoclonal IgM conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality Level
MQ100
Applications
Application
Milli-Mark Anti-CD57-FITC Antibody, clone TB01 is an antibody against CD57 for use in FC.
Key Applications
Flow Cytometry
Biological Information
Immunogen
A pool of neuroblastoma cell lines
Clone
TB01
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Specificity
Antibody recognizes Human CD57 antigen.
Isotype
IgMκ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_473366.1
Purification Method
Activated Sepharose
UniProt Number
Q9P2W7
Molecular Weight
110 kDa Observed
Product Usage Statements
Quality Assurance
Evaluated by flow cytometry using human PBMCs
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
