Millipore Anti-Ef5 Mouse Ab, 250ug, 2mg/Ml, Monoclonal

Millipore Anti-EF5 Mouse Antibody, 250 ug Net Content, 2 mg/mL, Monoclonal, Mouse Host Species, Liquid Form, -20 deg C, Cyanine 5 Conjugate, ELK3-51 Clone, Human, Mouse, Rat Species Reactivity, IgG1 Isotype. A number of imaging markers which target hypoxia exist and are widely used in research. EF5 (2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide) is a compound developed at the University of Pennsylvania by Dr. Cameron Koch and Dr. Sydney Evans. Upon injection into animal tissues, EF5 selectively binds to hypoxic cells and forms adducts. A mouse monoclonal antibody, clone ELK3-51, which is directly conjugated to Cyanine 5, is then used to selectively bind the EF5 adducts providing a sensitive and quanti-tative method to detect and measure tissue hypoxia in animal and human tumors, normal tissues and cells - Mill (Additional S&H or Hazmat Fees May Apply)