GenScript Sars-Cov-2 Spike Protein (Rbd, Avi & His Tag)-Hrp; 100ul

GenScript Sars-Cov-2 Spike Protein (Rbd, Avi & His Tag)-Hrp - GSCRPT (Additional S&H or Hazmat Fees May Apply)

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Description

Product Introduction

Species

SARS-CoV-2

Protein Construction

Spike RBD (Arg319-Ser591) Accession # P0DTC2	Avi	Poly-His
N-term		C-term

Conjugate

HRP

Biological Activity

This protein is validated to bind with human ACE2 (Cat. No. Z03516) in functional ELISA assay.

Expression System

Human Cells

Application

The optimal dilution ratio should be determined by the end user for specific applications.
ELISA 1:1000

Formulation

Supplied as a solution in PBS, pH 7.4, 0.1% ProClin 300.

Storage & Stability

Upon receiving, this product remains stable for up to 3 months at 2-8°C. Protect from light.

Background

Target Background	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. SARS-CoV-2 also known as 2019-nCoV, is a positive-sense single-stranded RNA virus and is believed to have zoonotic origins and has close genetic similarity to bat coronaviruses. The receptor binding domain (RBD) of spike protein of the SARS-CoV-2 virus binds Angiotensin-Converting Enzyme 2 (ACE2) to invade the host cells. Based on structural biology studies, the RBD can be oriented either in the up/standing or down/lying state with the up/standing state associated with higher pathogenicity.
Synonyms	SARS-CoV-2 SP RBD, 2019-nCoV S1 RBD, SARS-CoV-2 S1 RBD
References	1. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nature Microbiology. 5 (4): 536–544. 2. The proximal origin of SARS-CoV-2. Nature Medicine. 26 (4): 450–452. 3. The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections. Journal of Neuroimmune Pharmacology. 15 (3): 359–386.

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

Specifications